Robin Chi Group

Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore
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 Publications 
 2010
  
  
  
 13 
 2009-2002
 12

Guo, L.; Chi, Y.;  A. M. ; Guzei, I. A.; Parker, B. K. ; Gellman, S. H. "Stereospecific Synthesis of Conformationally Constrained γ-Amino Acids: New Foldamer Building Blocks That Support Helical Secondary Structure", J. Am. Chem. Soc, 2009, 131, 16018-16020. 

 

 11

Scroggins, T. S.; Chi, Y. Fréchet, J. M. J.” Polarity-Directed One-Pot Asymmetric Cascade Reactions Mediated by Two Catalysts in an Aqueous Bufferz”, Angew. Chem. Int. Ed., 2009, in press (VIP Paper)

 

 10

Chi, Y.; Scroggins, T. S.; Boz, E.; Fréchet, J. M. J. “Control of Aldol Reaction Pathways of Enolizable Aldehdyes with an Enzyme-Like Polymer Catalyst in Aqueous Environment”, J. Am. Chem. Soc, 2008, 130, 17287-17289.

 
 9

Chi, Y.; Scroggins, T. S.; Fréchet, J. M. J. “One-Pot Multi-Component Asymmetric Cascade Reactions Catalyzed by Soluble Star Polymers with Non-Interpenetrating Catalytic Cores”, J. Am. Chem. Soc., 2008, 130, 6322-6323.(Lawrence Berkeley National Laboratory 2008 Research Highlights)

 
 8

Chi, Y.; Guo, L.; Kopf, N. A.; Gellman, S. H. “Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2-Amino Acids”, J. Am. Chem. Soc., 2008, 130, 5608-5609. (Highlighted: C&E News, 2008, 86, 50-51; Synfacts 2008, 6, 0648.)

 
 7

Chi, Y.; et al. & Gellman, S. H. “Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes”, J. Am. Chem. Soc., 2007, 129, 6050-6055.

 

 6

Chi, Y.; Gellman, S. H. “Enantioselective Organocatalytic Aminomethylation of Aldehydes: A Role for Ionic Interactions and Access to β2-Amino Acids”, J. Am. Chem. Soc., 2006, 128, 6804-6805. (Highlighted: Angew. Chem. Int. Ed. 2006, 45, 7876-7880) 

 

 5

Peelen, T. J.; Chi, Y.; Gellman, S. H. “Enantioselective Organocatalytic Michael Additions of Aldehydes to Enones with Imidazolidinones: Cocatalyst Effects and Evidence for an Enamine Intermediate”, J. Am. Chem. Soc., 2005, 127, 11598-11599. (“Most-Accessed Article” in J. Am. Chem. Soc.; July-September, 2005).

 
 4

Chi, Y.; Gellman, S. H. “Diphenylprolinol Methyl Ether: A Highly Enantioselective Catalyst in Michael Addition of Aldehydes to Simple Enones”, Org. Lett., 2005, 7, 4253-4256. (Highlighted: Angew. Chem. Int. Ed. 2006, 45, 7876-7880)

 

 3

Chi, Y.; Peelen, T. J.; Gellman, S. H. “A Rapid 1H NMR Assay for Enantiomeric Excess of α-Substituted Aldehydes”, Org. Lett., 2005, 7, 3469-3472.

 2

Peelen T. J.; Chi, Y.; English, E. P.; Gellman, S. H. “Synthesis of 4,4-Disubstituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12- Helical β-Peptides”, Org. Lett., 2004, 6, 4411-4414.

 

 1

Wong, W-K.; Chen, X-P.; Guo, J-P.; Chi, Y-G.; Pan, W-X.; Wong, W-Y. “Synthesis, Structure and Catalytic Activity of Ruthenium Diaminodiphosphine Complexes”, J. Chem. Soc., Dalton Transaction, 2002, 1139-1146.

  
Patents  
 

3) Boz, E.; Chi, Y.; Diallo, M. S.; Frechet, J. M. J. ”Extraction of Anions from Solutions and Mixtures Using Hyberbranched Macromolecules”, 2008, US Patent Application No. 61/102,792

 

2) Chi, Y.; Guo, L.; Gellman, S. H. “Amino Acids and Catalytic Preparation Methods”, submitted in March 2008 (US Patent Application No: 2009/0264,676)

   

1) Chi, Y.; English, E. P.; Pomerantz, W. C.; Horne, W. S.; Guo, L.; Gellman, S. H. “Concise β2-Amino Acid Synthesis Via Organocatalytic Aminomethylation”, PCT Int. Appl. 2007, WO 2007112358. (US Patent Application No: 2008/0058,548 )